Exhaled breath condensate cytokine patterns in chronic obstructive pulmonary disease
نویسندگان
چکیده
منابع مشابه
Exhaled breath condensate analysis in chronic obstructive pulmonary disease.
The increasing focus on airway inflammation in the pathogenesis of chronic obstructive pulmonary disease (COPD) has led to development and evolution of tools to measure it. Direct assessment of airway inflammation requires invasive procedures, and hence, has obvious limitations. Non-invasive methods to sample airway secretions and fluids offer exciting prospects. Analysis of exhaled breath cond...
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Increasingly, exhaled breath condensate (EBC) is being used to sample airway fluid from the lower respiratory tract. EBC pH may be a biomarker of airway inflammation in chronic obstructive pulmonary disease (COPD). In this study, the reproducibility of EBC pH in COPD was investigated. A total of 36 COPD patients and 12 healthy nonsmoking subjects participated in several investigations: duration...
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sis of sputum cells, a semi-invasive technique, in patients with stable COPD of different severity. The authors show that 8-isoprostane concentrations in EBC are correlated with the dyspnea score and emphysematous changes which were assessed by high-resolution computerized tomography. No correlation between 8-isoprostane levels in EBC and lung function and COPD severity based on Global Initiati...
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BACKGROUND Inhalation of thermal water (TW) is traditionally used as part of the treatment of chronic obstructive pulmonary disease (COPD), but its benefit and mechanisms are controversial. We previously observed a reduced proportion of neutrophils in induced sputum after treatment with TW. OBJECTIVES The aim of this study was to determine whether inhalation of TW in COPD patients is associat...
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BACKGROUND Chronic obstructive pulmonary disease (COPD) is an important cause of occupational mortality in miners exposed to coal mine dust. Although the inflammatory mediators involved in COPD have not been defined, many studies have shown that inflammatory mediators such as reactive oxygen and nitrogen species are involved in orchestrating the complex inflammatory process in COPD. METHODS T...
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ژورنال
عنوان ژورنال: Respiratory Medicine
سال: 2005
ISSN: 0954-6111
DOI: 10.1016/j.rmed.2005.02.041